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1,8-dihydroxy-4-nitro-anthraquinone

Development stage
Unknown
Modality
Small Molecules
01

Overview

**1,8-Di-Hydroxy-4-Nitro-Anthraquinone** is a synthetic anthraquinone derivative characterized by two hydroxyl groups at positions 1 and 8 and a nitro group at position 4 on the anthraquinone core[2][3][6]. It is classified as a small molecule and belongs to the class of organic compounds known as anthraquinones[6]. The compound has been studied experimentally but is not approved for any therapeutic use in humans[6]. Its mechanism of action includes inhibition of casein kinase II subunit alpha (CSNK2A1), an enzyme involved in various cellular processes such as cell cycle control and apoptosis[6][8]. There are no current clinical indications or approvals for this compound.

Other names
4,5-dihydroxy-1-nitroanthracene-9,10-dione4,5-dihydroxy-1-nitro-9,10-anthraquinone9,10-anthracenedione, 4,5-dihydroxy-1-nitro-1m2p
02

Targets

CK2 (Casein kinase II subunit alpha)

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