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1-((pyridin-2-ylimino)methyl)naphthalen-2-ol
- Development stage
- Preclinical
- Lead developer
- University of Malakand
- Modality
- Small Molecules
01
Overview
1-((pyridin-2-ylimino)methyl)naphthalen-2-ol is an experimental Schiff base small molecule developed by researchers at the University of Malakand. It was synthesized through an aldol condensation reaction between 2-hydroxy-1-naphthaldehyde and 2-aminopyridine. Preclinical evaluations have demonstrated that the compound possesses dual therapeutic potential, exhibiting dose-dependent growth inhibition against human lung cancer (H-460) and breast cancer (MCF-7) cell lines. Additionally, it has shown antidepressant-like effects in animal models, specifically the elevated plus maze. The compound is currently in the early research phase, and its specific molecular targets have not been publicly disclosed.
- Other names
- 1-((pyridin-2-ylimino)methyl)naphthalen-2-ol
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