Drug intelligence / Profile preview

1-aminoindan

Development stage
Unknown
Lead developer
Teva Pharmaceutical Industries
Modality
Small Molecules
Administration
Not Established
01

Overview

**1-aminoindan** is a small bicyclic amine (C9H11N), existing as a racemic mixture of (R)- and (S)-enantiomers. The (R)-enantiomer is pharmacologically active and is a metabolite of rasagiline, an approved antiparkinsonian agent. 1-aminoindan demonstrates neuroactive properties and has been researched for its modulatory effects on catecholamine levels in the brain[8][2]. It is not in standard pharmaceutical use alone, but is relevant as a precursor or metabolite in medicinal chemistry and as a reference standard.

Other names
1-aminoindan1H-inden-1-amine, 2,3-dihydro-1-indanamineindan-1-ylamineindan1-ylamineindan 1-ylamine1-aminoinden1-iminoindane1-indamine(R)-(-)-1-aminoindan(S)-(+)-1-aminoindan
02

Targets

MAOB (Monoamine oxidase B)MAOA (Monoamine oxidase A)

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