1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide

1-butanoyl-N-(4-carbamimidoylbenzyl)-L-prolinamide is a synthetic small molecule peptidomimetic compound. It is structurally related to proline derivatives and contains a butanoylated proline core with a benzyl group substituted at the nitrogen, which itself carries a carbamimidoyl (guanidino) group. The compound has been studied as an experimental inhibitor of thrombin, acting as an anticoagulant by targeting the active site of this serine protease. Its primary mechanism involves direct inhibition of thrombin activity, thereby interfering with blood coagulation processes[5][10]. There are no approved indications or marketed formulations for this molecule; it remains in the experimental phase.

Other names

(2S)-1-butanoyl-N-((4-carbamimidoylphenyl)methyl)pyrrolidine-2-carboxamide(2S)-1-butanoyl-N-[(4-carbamimidoylphenyl)methyl]pyrrolidine-2-carboxamide(S)-1-butyryl-N-(4-carbamimidoylbenzyl)pyrrolidine-2-carboxamide hydrochloride