Drug intelligence / Profile preview

1-guanidino-4-(N-nitro-benzoylamino-L-leucyl-L-prolylamino)butane

Development stage
Unknown
Modality
Peptides, Small Molecules
01

Overview

1-Guanidino-4-(N-nitro-benzoylamino-L-leucyl-L-prolylamino)butane is a synthetic small molecule dipeptide derivative, structurally related to amino acids leucine and proline, with a guanidinium group and a nitrobenzoyl moiety. It is classified as an experimental compound and has not been approved for clinical use. The compound has been studied in the context of protein interactions, notably as a ligand in structural studies involving prothrombin/thrombin, suggesting it may act as an inhibitor or modulator of serine proteases involved in blood coagulation. However, no specific mechanism of action or therapeutic indication has been established for this molecule[1][3][7].

Other names
(2S)-N-{4-[(diaminomethylidene)amino]butyl}-1-[(2S)-4-methyl-2-[(4-nitrophenyl)formamido]pentanoyl]pyrrolidine-2-carboxamideN-(4-nitrobenzoyl)-L-leucyl-N-{4-[(diaminomethylene)amino]butyl}-L-prolinamideN-(4-NITROBENZOYL)-L-leucyl-N-(4-{[amino(imino)methyl]amino}butyl)-L-prolinamide

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