Drug intelligence / Profile preview

10% povidone iodine

Development stage
Unknown
Lead developer
Ain Shams University Maternity Hospital
Modality
Small Molecules
Administration
Topical
01

Overview

10% povidone iodine is a broad-spectrum antiseptic solution composed of a stable chemical complex of polyvinylpyrrolidone (povidone) and elemental iodine. It is widely used for skin and mucosal disinfection due to its potent antimicrobial activity against bacteria, viruses, fungi, and protozoa. In clinical research conducted by Ain Shams Maternity Hospital, this 10% solution is specifically utilized for preoperative vaginal cleansing in women undergoing cesarean sections. The primary objective of this intervention is to reduce the risk of post-cesarean endometritis by decreasing the microbial load in the vaginal canal prior to surgery. The drug functions by the slow release of free iodine, which acts as a non-specific oxidizing agent that destroys essential microbial components, including proteins and nucleic acids.

Brand names
Betadine
Other names
povidone iodinePVP-Iiodopovidonepolyvinylpyrrolidone-iodine
02

Targets

DNA

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