11α-hydroxycanrenone methyl acetate

11α-hydroxycanrenone methyl acetate is a steroidal small molecule and active pharmaceutical ingredient (API) intermediate developed and manufactured by Jiangsu Jiaerke Pharmaceuticals. It serves as a critical structural precursor in the industrial synthesis of eplerenone, a selective mineralocorticoid receptor antagonist (MRA) used for the management of hypertension and chronic heart failure. The compound is part of the specialized steroidal pipeline at Jiangsu Jiaerke, which focuses on the production of corticosteroid and progestogen derivatives. As an intermediate, it is primarily utilized in the multi-step chemical transformation process required to produce finished steroidal drug products.

Other names

11α-hydroxycanrenone methyl ester11α-hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid methyl esterMethyl 11α-hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylate