Drug intelligence / Profile preview

11-valent recombinant human papillomavirus vaccine

Development stage
Unknown
Lead developer
Sinopharm
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The **11-valent recombinant human papillomavirus vaccine** is an investigational prophylactic HPV vaccine produced in *Hansenula polymorpha*. It is intended to induce humoral and cellular immune responses against 11 HPV antigens, supporting prevention of HPV infection and HPV-associated cervical precancerous lesions, genital warts, and related anogenital disease. It has been evaluated in Chinese females using a three-dose intramuscular regimen at months 0, 2, and 6, with Phase III clinical evaluation registered in women aged 9–45 years.

Other names
11-valent recombinant HPV vaccine11-valent recombinant human papilloma virus vaccine11-valent recombinant human papillomavirus vaccine11-valent recombinant human papillomavirus vaccine (Hansenula polymorpha)11-valent recombinant human papillomavirus vaccine (Hansenulapolymorpha)
02

Targets

HPV L1 (Human papillomavirus L1 capsid protein)HPV16 E7 (Human papillomavirus 16 E7 protein)

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