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1100 ppm as MFP
- Development stage
- Unknown
- Lead developer
- Procter & Gamble
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
1100 ppm as MFP is a fluoride-containing dentifrice (toothpaste) formulated with 1,100 parts per million of fluoride delivered as sodium monofluorophosphate (MFP) in a silica abrasive base. Developed by Procter & Gamble, it is used as a reference or comparator product in clinical research evaluating anticaries efficacy. The active ingredient, sodium monofluorophosphate, acts on tooth enamel by promoting remineralization and inhibiting demineralization, with its biological target being dental enamel hydroxyapatite. It is indicated for the prevention of dental caries and has been evaluated in clinical trials, including a Phase 1 crossover study (NCT06735235) assessing salivary fluoride clearance in healthy adults.
- Other names
- 1,100 ppm F as MFP1100 ppm F as MFP1100 ppm MFP dentifrice1100 ppm MFP toothpastesodium monofluorophosphate 1100 ppm
02
Targets
Hydroxyapatite
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