111In-DTPA-cT84.66

**111In-DTPA-cT84.66** is an investigational radioimmunoscintigraphy agent comprising the chimeric human/murine IgG1 anti-carcinoembryonic antigen antibody cT84.66, conjugated to diethylenetriaminepentaacetic acid and labeled with indium-111. The antibody selectively binds carcinoembryonic antigen-related cell adhesion molecule 5 on CEA-producing tumors, enabling SPECT imaging, biodistribution assessment, and radiation-dosimetry estimation. It was administered intravenously in clinical studies, including as a 5 mCi/5 mg imaging dose in patients with localized or limited metastatic CEA-producing colorectal cancer undergoing surgical resection. Imaging was used to evaluate tumor targeting and to identify patients potentially suitable for subsequent yttrium-90-cT84.66 radioimmunotherapy. ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/9867150/))

Other names

111In-cT84.66111In-labeled cT84.66indium 111-cT84.66 monoclonal antibodyindium111-cT84.66 monoclonal antibodyindium-111-cT84.66 monoclonal antibodyindium-111-labeled cT84.66indium111-labeled cT84.66indium 111-labeled cT84.66