Drug intelligence / Profile preview

123 Complete Cold Cough and Flu

Development stage
Unknown
Lead developer
Algorithm
Modality
Small Molecules
Administration
Oral
01

Overview

123 Complete Cold Cough and Flu is an over-the-counter combination medication developed and marketed by Algorithm for the symptomatic relief of the common cold, cough, and influenza. The product is packaged as a combination of Day and Night tablets. The Day tablets contain paracetamol (acetaminophen) for pain and fever relief, phenylephrine hydrochloride as a nasal decongestant, and dextromethorphan hydrobromide as a cough suppressant. The Night tablets contain the same three active ingredients with the addition of carbinoxamine maleate, a first-generation antihistamine that provides relief from runny nose and sneezing while promoting sleep. Together, these components target cyclooxygenase enzymes (COX-1 and COX-2), alpha-1 adrenergic receptors, sigma-1 receptors, NMDA receptors, and histamine H1 receptors to address multi-symptom respiratory tract infections.

Brand names
123 Complete Cold Cough and Flu
Other names
123 Complete Cold, Cough and Flu123 Complete Cold, Cough and Flu Primary Care
02

Targets

ADRA1A (α1A)COXHRH1 (Histamine H1 Receptor)

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