Drug intelligence / Profile preview

123I-AV151

Development stage
Phase 1
Lead developer
Institute for Neurodegenerative Disorders
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

123I-AV151 is a radiopharmaceutical imaging agent that incorporates Iodine-123. It is designed to detect beta-amyloid deposition in the brain, serving as a diagnostic tool for conditions such as Alzheimer's disease. The agent is administered via bolus injection and its distribution is visualized using Single-Photon Emission Computed Tomography (SPECT) to identify and quantify amyloid plaques.

Other names
[123I]MNI-330123-I MNI-330
02

Targets

Aβ (Amyloid-beta peptides and aggregates)

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