Drug intelligence / Profile preview

12R-HEPE

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

12R-HEPE is a hydroxy derivative of eicosapentaenoic acid (EPA) with the molecular formula C20H30O3. It is classified as a HEPE (hydroxyeicosapentaenoic acid) and has been reported to occur naturally in the red alga Murrayella periclados. The compound features a hydroxyl group at the 12-carbon position with R stereochemistry and contains five double bonds in a specific configuration (5Z,8Z,10E,14Z,17Z). 12R-HEPE is found as an ingredient in some omega-3 formulations like Luvira, where it is combined with other omega-3 fatty acids for dietary supplementation.

Other names
(12R)-12-hydroxyeicosapentaenoic acid12(R)-HEPE12-Hydroxyeicosapentaenoic acid, (12R)-12R-hydroxy-5Z,8Z,10E,14Z,17Z-eicosapentaenoic acid(5Z,8Z,10E,12R,14Z,17Z)-12-hydroxyicosa-5,8,10,14,17-pentaenoic acid5,8,10,14,17-Eicosapentaenoic acid, 12-hydroxy-, (5Z,8Z,10E,12R,14Z,17Z)-

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