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**13-Acetylphorbol** is a naturally occurring organic compound classified as a phorbol ester, specifically an acetylated derivative of the diterpene phorbol. It is found in certain plant species such as *Croton tiglium*. Phorbol esters are known for their biological activity, notably as potent activators of protein kinase C (PKC), which plays a key role in cell signaling pathways related to proliferation, differentiation, and apoptosis. Due to its strong irritant properties and ability to modulate PKC activity, compounds like 13-acetylphorbol have been widely used in biomedical research but are not approved pharmaceuticals or dietary supplements[1][2][6].
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