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131I-DGT-207

Development stage: Preclinical
Lead developer: dGenThera
Modality: Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptide-Drug Conjugates → Peptide Conjugates → Peptides

Overview

131I-DGT-207 is a preclinical-stage targeted radiotherapeutic being developed by dGenThera for the treatment of undisclosed receptor-positive cancers. The drug is a bioligand-tag conjugate designed to deliver the radioisotope Iodine-131 specifically to tumor cells expressing an undisclosed receptor target. dGenThera's proprietary chemistry platform utilizes engineered stable carbon-halogen bonds to improve dosimetry accuracy, enhance patient stratification, and reduce off-target toxicity. Preclinical biodistribution data for 131I-DGT-207 has demonstrated superior performance compared to both chelated metal targeted radiotherapeutics and other Iodine-131 targeted radiotherapeutics designed for the same target.

Other names: Iodine-131 DGT-207Iodine131 DGT-207Iodine 131 DGT-207

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