Drug intelligence / Profile preview

13C-glucose

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intravenous
01

Overview

13C-glucose is a non-radioactive glucose isotopomer in which one or more carbon atoms are replaced by the stable carbon-13 (13C) isotope. It has potential imaging applications and is used as a tracer in metabolic studies. Different forms exist based on which carbon positions are labeled (e.g., [1-13C]glucose, [2-13C]glucose, [3-13C]glucose, or uniformly labeled [13C6]glucose). 13C-glucose breath tests are used as a non-invasive method to evaluate glucose metabolism, with different carbon positions providing insights into specific metabolic pathways. For example, the [1-13C]glucose breath test is suitable for evaluating late-stage diabetes, while the [2-13C]glucose breath test is ideal for early-stage diabetes detection.

Other names
Uniformly-labeled [13C]glucoseD-Glucose-13C6D-Glucose13C6D-Glucose 13C6D-Glucose-1-13CD-Glucose1-13CD-Glucose 1-13CD-Glucose-2-13CD-Glucose2-13CD-Glucose 2-13CD-Glucose-3-13CD-Glucose3-13CD-Glucose 3-13CD-Glucose-4-13CD-Glucose4-13CD-Glucose 4-13CD-Glucose-6-13CD-Glucose6-13CD-Glucose 6-13CD-Glucose-ul-13CD-Glucose-ul13CD-Glucose-ul 13CD-((13)C6)glucose
02

Targets

GCK (Glucokinase)GLUT (Glucose transporter family)

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