13C-labeled docosahexaenoic acid triglyceride

**13C-labeled TG-DHA** is a stable isotope-labeled triglyceride form of docosahexaenoic acid (DHA) utilized in clinical research to investigate the metabolic fate and bioavailability of omega-3 fatty acids. Developed by **Hospices Civils de Lyon**, this compound is specifically used in studies targeting **Alzheimer's disease** and age-related cognitive decline to identify the most effective lipidic carriers for delivering DHA to the brain. DHA is a critical structural component of neuronal membranes and serves as a ligand for several nuclear and membrane-bound receptors, including **Free fatty acid receptor 4 (GPR120)** and **Peroxisome proliferator-activated receptor gamma (PPARG)**. By incorporating a Carbon-13 label, researchers can track the incorporation of the fatty acid into plasma lipids and blood cells using mass spectrometry, providing insights into the optimal dietary or therapeutic strategies for maintaining brain health in elderly populations.

Other names

13-C labeled TG-DHA-Hospices Civils de Lyon-Alzheimer's disease13C-labeled docosahexaenoic acid triglyceride[13C]-TG-DHA13C-labeled DHA-TG