Drug intelligence / Profile preview

15-valent recombinant human papillomavirus vaccine

Development stage
Phase 1
Lead developer
Shanghai Bovax Biotechnology
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**15-valent recombinant human papillomavirus vaccine** is an investigational prophylactic HPV vaccine developed by Shanghai Bovax Biotechnology and Chongqing Bovax Biopharmaceutical. It consists of recombinant virus-like particles formed from the HPV major capsid protein L1 for HPV types 6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68, expressed in *Hansenula polymorpha* and adsorbed to an aluminium adjuvant. The noninfectious L1 virus-like particles are intended to induce type-specific neutralizing antibodies that prevent infection with included HPV types and thereby prevent HPV-associated genital warts, precancerous lesions, and cancers. The program is in Phase 2 clinical development in healthy Chinese participants aged 9–45 years. ([bovaxbio.com](https://www.bovaxbio.com/en/sys-pd/4.html))

Other names
15-valent HPV vaccinerecombinant 15-valent human papillomavirus vaccinerecombinant15-valent human papillomavirus vaccinerecombinant-15-valent human papillomavirus vaccine
02

Targets

HPV L1 (Human papillomavirus L1 capsid protein)

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