Drug intelligence / Profile preview

18-methyl-19-nortestosterone

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Subcutaneous
01

Overview

18-methyl–19-nortestosterone is a synthetic steroidal compound classified as an androgen and anabolic steroid. It is structurally related to nandrolone (19-nortestosterone) with a methyl group at the C18 position. The compound has been studied primarily as an experimental or reference substance and is not approved for medical use. Its mechanism of action, like other nortestosterone derivatives, involves agonism at the androgen receptor, leading to anabolic and androgenic effects. Esters and derivatives of this molecule have demonstrated progestogenic activity in animal models, including ovulation inhibition when administered orally or subcutaneously[1][2][5]. It serves as a parent structure for several clinically relevant progestins such as levonorgestrel.

Other names
13beta-ethyl-17beta-hydroxygon-4-en-3-one13-beta-ethyl-17beta-hydroxygon-4-en-3-oneGon-4-en-3-one, 13‑ethyl‑17‑hydroxy-, (17beta)-LEVONORGESTREL IMPURITY K [EP IMPURITY]
02

Targets

PR (Progesterone receptor)AR (Adrenergic receptors)

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