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188Re-rhenium resin
- Development stage
- Unknown
- Lead developer
- OncoBeta
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
- Administration
- Topical
01
Overview
188Re-rhenium resin (commercially known as Rhenium-SCT) is a non-invasive, unsealed therapeutic radiopharmaceutical developed by OncoBeta for the treatment of non-melanoma skin cancers (NMSCs). It consists of the high-energy beta-emitting radioisotope rhenium-188 (188Re) in the form of insoluble dirhenium-heptasulfide microparticles embedded in a synthetic acrylic resin matrix. The radioactive paste is applied topically over a protective barrier foil directly onto the lesion, delivering localized, high-dose beta radiation that penetrates up to 2–3 mm into the skin. This targeted radiation destroys cancer cells while sparing deeper healthy tissues.
- Brand names
- Rhenium-SCT
- Other names
- 188Re resin188Re-resin188Re-rhenium resin188Rhenium SCT188Rhenium-SCTdirhenium heptasulfidedirhenium-heptasulfiderhenium-188 pasterhenium188 pasterhenium 188 pasterhenium-188 resinrhenium188 resinrhenium 188 resin
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