Drug intelligence / Profile preview

18F-2-fluoro-2-deoxy-D-glucose

Development stage
Unknown
Lead developer
Eastern Health
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

18F-2-fluoro-2-deoxy-D-glucose (18F-FDG) is a radiopharmaceutical glucose analog used in positron emission tomography (PET) imaging. Developed and produced locally by Eastern Health in Newfoundland and Labrador, Canada, this specific formulation is intended to improve patient access to diagnostic imaging within the province. The molecule is transported into cells by glucose transporters (GLUTs) and subsequently phosphorylated by hexokinase. Due to the substitution of a hydroxyl group with a fluorine-18 isotope at the C-2 position, the resulting 18F-FDG-6-phosphate cannot be further metabolized via glycolysis and remains trapped within the cell. This metabolic trapping allows for the visualization and quantification of glucose consumption in tissues, making it a vital tool for the diagnosis and staging of various conditions, including malignant tumors, neurological disorders, and inflammatory diseases.

Other names
fludeoxyglucose F 182-deoxy-2-(18F)fluoro-D-glucosefluorodeoxyglucose18F-2-fluoro-2-deoxy-D-glucose-Eastern Health, Canada
02

Targets

GLUT (Glucose transporter family)GCK (Glucokinase)

Beyond the preview

Go deeper on 18F-2-fluoro-2-deoxy-D-glucose.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on 18F-2-fluoro-2-deoxy-D-glucose.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call