Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
18F-ASIS
- Development stage
- Phase 1
- Lead developer
- Rigshospitalet
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Peptides
- Administration
- Intravenous
01
Overview
18F-ASIS is a positron emission tomography (PET) radiotracer designed to image the expression of Tissue Factor (TF) in various cancers, including breast, lung, pancreatic, cervical, and ovarian cancers. Developed by Rigshospitalet in Denmark, the tracer utilizes a fluorine-18 labeled version of active site-inhibited factor VIIa (ASIS), which binds with high affinity and specificity to TF. Tissue Factor is often overexpressed in aggressive tumors and is associated with poor prognosis and tumor progression. 18F-ASIS serves as a diagnostic tool to evaluate tumor aggression and as a potential companion diagnostic to identify patients eligible for TF-targeted therapies, such as tisotumab vedotin.
- Other names
- 18F-labeled active site-inhibited factor VIIa18F-ASIS PET
02
Targets
F3 (Tissue factor)
Beyond the preview
Go deeper on 18F-ASIS.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on 18F-ASIS.