Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
18F-DTPA
- Development stage
- Preclinical
- Lead developer
- Technical University of Munich
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
18F-DTPA is a fluorine-18-labeled radioligand developed by the Technical University of Munich (TUM) as part of a novel bioorthogonal positron emission tomography (PET) reporter gene system (DTPA-R). The system consists of a membrane-anchored reporter protein, DTPA-R (comprising the engineered lipocalin Anticalin CL31d), which binds the 18F-DTPA lanthanide complex with picomolar affinity. 18F-DTPA is designed for non-invasive, quantitative, and high-contrast whole-body PET imaging to track the biodistribution, proliferation, and migration of advanced therapies, such as chimeric antigen receptor (CAR) T-cells, adeno-associated virus (AAV) gene therapies, and human induced pluripotent stem cell (hiPSC)-derived cardiac progenitors.
- Other names
- [18F]F-DTPA[18F]F-DTPA*Tb[18F]F-DTPA•Tb[18F]F-DTPA•TbIII[18F]F-Nic-Glu2-PEG4-CHX-A''-DTPA•metal[18F]F-Nic-Glu2-PEG4-CHX-A''-DTPA•Tb18F-DTPA-Tb18F-labeled DTPA
Beyond the preview
Go deeper on 18F-DTPA.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on 18F-DTPA.