Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
18F-FAA
- Development stage
- Preclinical
- Modality
- Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Positron Emitters → Radiopharmaceuticals, Small Molecules
- Administration
- Intravenous
01
Overview
18F-FAA is a radiolabeled fatty acid analog developed as a positron emission tomography (PET) tracer for the assessment of myocardial fatty acid metabolism. Abnormalities in myocardial fatty acid metabolism are implicated in various cardiac diseases such as obesity, diabetes mellitus, and dilated cardiomyopathy. The compound is synthesized by labeling a suitable precursor with fluorine-18 and purified via HPLC. In preclinical studies using animal models (e.g., ZDF lean rats), 18F-FAA demonstrated favorable imaging characteristics for the myocardium and exhibited tracer kinetics similar to those of established tracers like 11C-palmitate. Its slower early clearance compared to 11C-palmitate suggests potential advantages for clinical PET imaging of altered myocardial fatty acid metabolism[6][9].
- Other names
- 18F-fluoro fatty acid analogF-18 fatty acid analogF18 fatty acid analogF 18 fatty acid analog
02
Targets
CD36 (CD36 antigen)SLC7A1 (Cationic amino acid transporter 1)FABP (Fatty acid-binding protein family)LacS (Lactose permease)
Beyond the preview
Go deeper on 18F-FAA.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on 18F-FAA.