Drug intelligence / Profile preview

18F-FlutraTate

Development stage
Preclinical
Lead developer
TetraKit Technologies
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Peptides
Administration
Intravenous
01

Overview

18F-FlutraTate (also known as OCT-TBD) is a preclinical-stage, fluorine-18 (18F)-labeled radiopharmaceutical diagnostic agent developed by TetraKit Technologies. It is designed as a positron emission tomography (PET) imaging tracer targeting the somatostatin receptor (SSTR) for the detection and management of neuroendocrine tumors (NETs). The agent utilizes an octreotate-related targeting ligand conjugated to a fluorine-18 beta-plus emitter, leveraging TetraKit's proprietary tetrazine-based click chemistry platform to achieve rapid and efficient radiolabeling.

Brand names
FlutraTate
Other names
18F-flutratate
02

Targets

SSTR2 (Somatostatin receptor type 2)SSTR5 (Somatostatin receptor 5)SSTR3 (Somatostatin receptor 3)

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