Drug intelligence / Profile preview

18F-LNC1019

Development stage
Preclinical
Lead developer
LNC Pharma
Modality
Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

18F-LNC1019 is a diagnostic radiopharmaceutical developed by LNC Pharma for use in Positron Emission Tomography (PET) imaging. It is composed of a targeting ligand labeled with the radioisotope fluorine-18 (18F) that specifically binds to the Gastrin-Releasing Peptide Receptor (GRPR). GRPR is a G protein-coupled receptor that is frequently overexpressed in various malignancies, most notably in prostate and breast cancers. By targeting these receptors, 18F-LNC1019 enables the non-invasive visualization, characterization, and localization of GRPR-positive tumors, facilitating improved diagnosis and staging. The agent is currently in the preclinical stage of development.

02

Targets

GRPR (Gastrin-releasing peptide receptor)

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