Drug intelligence / Profile preview

18F-MD-PSMA

Development stage
Preclinical
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

**18F-MD-PSMA** is an investigational **fluorine-18 labeled PSMA-targeted PET radiotracer** for molecular imaging of **prostate cancer**. It is a small-molecule radiopharmaceutical designed to bind **prostate-specific membrane antigen**, which is highly expressed on many prostate cancer cells, enabling PET/CT detection of primary, recurrent, or metastatic lesions. Published clinical reports describe its use in patients with **biochemical relapse after prior prostate cancer treatment** and in **initial staging of intermediate- and high-risk prostate cancer**, with performance reported as favorable versus choline PET in at least one retrospective study. The name itself indicates a multidentate PSMA imaging-agent scaffold, but publicly available sources provide limited detail on the exact chemical identity, commercial sponsor, or manufacturing organization.

Other names
MD-PSMAMulti-dentate PSMA imaging agent
02

Targets

PSMA (Prostate-specific membrane antigen)

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