18F-P10A1910

18F-P10A1910 is a fluorine-18 labeled radiopharmaceutical designed as a positron emission tomography (PET) imaging tracer. It specifically targets phosphodiesterase 10A (PDE10A), an enzyme primarily localized in the striatum of the brain that regulates intracellular signaling by hydrolyzing cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). The tracer is utilized in clinical research to quantify PDE10A expression levels and distribution in the central nervous system, particularly in the context of metabolic disorders like obesity and neuropsychiatric conditions. By binding to PDE10A, 18F-P10A1910 allows for non-invasive visualization and measurement of the enzyme's density, which may correlate with body mass index (BMI), bone density, and other metabolic parameters.

Other names

[18F]P10A1910