Drug intelligence / Profile preview

18F-raltegravir

Development stage
Phase 1
Lead developer
Merck
Modality
Small Molecules, Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

18F-raltegravir is a radiopharmaceutical consisting of the HIV integrase inhibitor raltegravir labeled with radioactive fluorine-18. It is used as a PET imaging agent to study the distribution of raltegravir in the body, particularly in HIV-infected patients. This allows researchers to track how the drug distributes through tissues and potential HIV reservoirs, providing valuable information about antiretroviral drug penetration.

Other names
5G8B507W3F1236352-56-9
02

Targets

Integrase allosteric pocket (HIV)

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