19(R)-hydroxyprostaglandin E2

19(R)-hydroxyprostaglandin E2 is a naturally occurring lipid mediator and an analog of Prostaglandin E2 (PGE2), primarily identified in the semen of primates, including humans. It functions as a potent and selective agonist for the Prostaglandin E2 receptor EP2 subtype. As a small molecule, it is widely utilized as a chemical research tool to investigate the physiological and pathological roles of the EP2 receptor pathway, particularly its involvement in smooth muscle relaxation, inflammation, vascular tone regulation, and immune response modulation. The compound is commercialized by specialized chemical suppliers such as Cayman Chemical and MedChemExpress for laboratory research purposes only and is not approved for human or veterinary therapeutic applications.

Other names

19(R)-hydroxy PGE219(R)-OH PGE211α,15S,19R-trihydroxy-9-oxo-prosta-5Z,13E-dien-1-oic acid19(R)-hydroxy-PGE2