2,3-dihydroxybenzoylserine

**2,3-Dihydroxybenzoylserine** is a small molecule and a derivative of L-serine in which the amino group is acylated with a 2,3-dihydroxybenzoyl group. It is naturally produced by certain bacteria such as *Escherichia coli* as part of their siderophore biosynthesis pathways. Siderophores are molecules that bind and transport iron in microorganisms. Specifically, this compound serves as a building block for catecholate-type siderophores like enterobactin and related analogs. Its primary biological function involves chelation of ferric iron (Fe^3+), facilitating iron acquisition under conditions of low environmental iron availability[1][5][4]. The mechanism involves strong binding to Fe^3+, forming stable complexes that can be transported into bacterial cells via specific receptors.

Other names

N-(2,3-dihydroxybenzoyl)-L-serine2,3-DHBS2,3-Dihydroxy-N-benzoyl-L-serineSerine, N-(2,3-dihydroxybenzoyl)-2-(2,3-dihydroxy-benzoylamino)-3-hydroxy-propionic acid