Drug intelligence / Profile preview

2,4,6-Triaminoquinazoline

Development stage
Unknown
Modality
Small Molecules
01

Overview

**2,4,6-Triaminoquinazoline** is a synthetic small molecule belonging to the class of quinazolinamines. It features a quinazoline core substituted with amino groups at positions 2, 4, and 6. The compound has been studied primarily as an experimental chemical probe and is not approved for clinical use. Quinazoline derivatives are known for their diverse biological activities; however, there is no evidence that this specific compound has reached advanced preclinical or clinical development as a pharmaceutical agent. Its mechanism of action and pharmacological targets have not been clearly established in the literature[1][2][3]. Some related substituted quinazolines have shown activity as inhibitors of ABC transporter proteins (such as ABCG2), which are implicated in multidrug resistance in cancer cells[5], but there is no direct evidence that unmodified 2,4,6-triaminoquinazoline itself acts on these targets.

Other names
quinazoline-2,4,6-triamine2,4,6-Triaminoquinazoline13741-90-72,4,6-qunazolinetriamine

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