2,4-diamino-5-phenyl-6-ethylpyrimidine

**2,4-Diamino–5–phenyl–6–ethylpyrimidine** is a synthetic small molecule belonging to the aminopyrimidine class of heterocyclic aromatic organic compounds. It has the molecular formula C12H14N4 and a molecular weight of approximately 214.27 g/mol[1][2][9]. The compound is structurally related to pyrimethamine but lacks the para-chloro substituent on the phenyl ring[5]. It has been studied as an experimental agent and is not approved for clinical use in any country[1][7]. Its mechanism of action includes inhibition of thymidylate synthase based on biochemical studies and structural data from ligand-protein complexes[7]. No approved indications or marketed formulations are known.

Other names

2,4-diamino-6-ethyl-5-phenylpyrimidinediamino-5-phenyl-6-ethylpyrimidine, 2,4-6-Ethyl–5–phenyl–2,4-pyrimidinediamine