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2,6-diamino-8-(1h-imidazol-2-ylsulfanylmethyl)-3h-quinazoline-4-one
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule belonging to the quinazolinamine class. It is an experimental compound that acts as an inhibitor of tRNA–guanine transglycosylase (TGT), an enzyme involved in tRNA modification and implicated in the pathogenicity of Shigella species. The compound has been studied structurally for its binding to TGT and serves as a scaffold for structure-based drug design targeting this enzyme[4][6]. There are no approved indications or clinical trials reported for this molecule.
- Other names
- 2,6-diamino-8-(1h-imidazol-2-ylsulfanylmethyl)-3h-quinazoline-4-one2,6-diamino-8-(1H-imidazol-2-Ylsulfanylmethyl)-3H-quinozalinone2,6-diamino-8-(1H-imidazol‑2‑ylsulfanyl)methyl‑3,4‑dihydroquinazolin‑4‑one
02
Targets
TGT (tRNA-guanine transglycosylase (Zymomonas mobilis))
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