2-(1H-pyrazol-3-yl)-1H-benzimidazole

**2-(1H-pyrazol-3-yl)-1H-benzimidazole** is a synthetic small molecule compound featuring a benzimidazole core fused to a pyrazole ring. It is primarily characterized as an experimental Aurora kinase A inhibitor, with reported activity against this target in biochemical assays (IC50 ≈910 nM). Aurora kinase A is involved in the regulation of mitosis and cell division, making inhibitors of this enzyme potential candidates for anticancer drug development. However, there are no approved indications or clinical trials beyond preclinical research for this compound[1][4][8]. No commercial brand names or marketed formulations exist.

Other names

2-(1H-pyrazol-5-yl)-1H-benzimidazole2-(1H-pyrazol-3)-1H-benzoimidazole2-(1H-pyrazol-3-yl)-1H-benzo[d]imidazolepyrazole-benzimidazole, 16pyrazolylbenzimidazole