2-(2-chloropyridin-4-yl)-4-methyl-1H-isoindole-1,3(2H)-dione

**2-(2-chloropyridin-4‑yl)-4‑methyl‑1H‑isoindole‑1,3(2H)‑dione** is a synthetic small molecule belonging to the phthalimide class of organic compounds[2]. It has been studied as an inhibitor of bacterial thymidylate synthase (TS), with evidence suggesting it binds specifically to bacterial TS and exhibits higher affinity for the bacterial enzyme compared to the human counterpart. This selectivity makes it a potential lead compound for antibacterial drug development targeting thymidylate synthase in pathogenic bacteria[5]. The compound is primarily referenced in research and structural biology contexts and does not have established pharmaceutical use or marketed formulations.

Other names

2-(2-chloropyridin-4-yl)-4-methylisoindole-1,3-dione2-(2-chloropyridin-4-yl)-4-methyl-2,3-dihydro-1H-isoindole-1,3-dione