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2-Aminoadenosine is a synthetic purine nucleoside analog structurally related to adenosine. It features an amino group at the C-2 position of the adenine ring. This modification allows it to form three Watson-Crick type hydrogen bonds in nucleic acid structures and increases the stability of double-stranded helices[6]. As a nucleoside analog, it has been studied as an inhibitor or substrate for adenosine kinase from Mycobacterium tuberculosis and is used in chemical synthesis for modified guanosines[6]. Its pharmacological activity is experimental; there are no approved medical indications or clinical uses reported for this compound[1][4][6].
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