Drug intelligence / Profile preview

2-aminoethanesulfonic acid injection

Development stage
Unknown
Lead developer
Nanjing Yoko Biomedical
Modality
Small Molecules
Administration
Intravenous
01

Overview

2-Aminoethanesulfonic Acid Injection is an intravenous formulation of taurine (2-aminoethanesulfonic acid), a naturally occurring non-protein beta-amino acid with antioxidant, anti-inflammatory, and cytoprotective properties. It is being developed by Nanjing Yoko Biomedical as a component of a Compound Edaravone Injection intended for the treatment of acute ischemic stroke. In clinical trials, the standalone 2-Aminoethanesulfonic Acid Injection has been evaluated in healthy volunteers to assess the pharmacokinetic drug-drug interactions between taurine and edaravone. Taurine acts as an agonist at GABA-A and glycine receptors, helping to mitigate glutamate-induced excitotoxicity, reduce oxidative stress, and maintain intracellular calcium homeostasis during ischemic events.

Other names
2-aminoethanesulfonic acidtaurinetaurine injection
02

Targets

GABRR (GABA-A receptor subunit rho)Glycine receptor

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