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2-dimethylamino-4,5,6,7-tetrabromo-1H-benzimidazole
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
A synthetic small molecule benzimidazole derivative and potent inhibitor of casein kinase II (CK2), a serine/threonine protein kinase involved in cell growth and survival. It is also reported to inhibit dual specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2). The compound has been studied primarily as a research tool for probing CK2 function and signaling pathways in cancer biology. It is not approved for clinical use and remains an experimental agent[1][5][9].
- Other names
- DIMETHYL-(4,5,6,7-TETRABROMO-1H-BENZOIMIDAZOL-2-YL)-AMINE4,5,6,7-tetrabromo-N,N-dimethyl-1H-benzimidazol-2-amine4,5,6,7-tetrabromo-N,N-dimethyl-benzo[d]imidazol-2-amino4,5,6,7-tetrabromo-N,N-dimethylbenzoimidazolylamineCHEMBL376505CHEMBL-376505CHEMBL 376505
02
Targets
NQO2 (Ribosyldihydronicotinamide dehydrogenase [quinone])CSNK2A2 (Casein kinase II subunit alpha prime)
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