2010-11 trivalent inactivated influenza vaccine

The 2010-11 trivalent inactivated influenza vaccine (TIV) is a seasonal injectable vaccine formulated to protect against three strains of influenza virus predicted to be most prevalent during the 2010–2011 flu season. The formulation includes two influenza A subtypes (H1N1 and H3N2) and one influenza B strain. It is an inactivated (killed-virus), split or subunit virion vaccine that stimulates the immune system to produce antibodies against hemagglutinin antigens from these strains. The primary mechanism of action is induction of humoral immunity via neutralizing antibodies targeting viral hemagglutinin proteins. This class of vaccines does not contain live virus and cannot cause influenza infection. Multiple brands were licensed for use in various age groups during this season; some formulations were standard dose while others (e.g., Fluzone High-Dose) contained higher antigen content for older adults[1][2][3][4].

Brand names

FluzoneFluzone High-DoseFluLavalAfluriaFluvaxFluvax Junior

Other names

2010-11 TIV2010-11 seasonal influenza vaccine