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The 2010-11 trivalent inactivated influenza vaccine is a seasonal biologic used for the prevention of influenza infection. Formulated for the 2010-2011 Northern Hemisphere season, it contains inactivated viral components from three influenza strains: two influenza A subtypes (H1N1 and H3N2) and one influenza B lineage (specifically the B/Victoria lineage for this season). The vaccine functions by stimulating the immune system to produce neutralizing antibodies against the viral surface proteins hemagglutinin and neuraminidase. This specific vaccine was the subject of the TITRE IIB Follow-Up study conducted by the British Columbia Centre for Disease Control, which investigated the immune response in children to a second dose of the B/Victoria lineage following previous immunization with a B/Yamagata-containing vaccine in the 2008-09 season.
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