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26价肺炎球菌结合疫苗

Development stage: Unknown
Lead developer: Zhifei Biological
Modality: Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

The 26-valent pneumococcal conjugate vaccine (PCV26) is a multivalent conjugate vaccine developed by Beijing Zhifei Lvzhu Biopharmaceutical, a subsidiary of Zhifei Biotech, for the prevention of pneumococcal disease. It is designed to induce active immunization against 26 serotypes of *Streptococcus pneumoniae* by conjugating pneumococcal capsular polysaccharide antigens to a carrier protein, which enhances immunogenicity particularly in infants and elderly populations. The vaccine is currently in Phase I/II clinical trials in China for individuals aged 2 months and older, and in Phase I clinical trials in Australia for adults aged 60 and older.

Other names: 26-valent Pneumococcal Conjugate Vaccine26价肺炎结合疫苗

Targets

10A CPS (Streptococcus pneumoniae serotype 10A capsular polysaccharide)PPS3 (Streptococcus pneumoniae serotype 3 capsular polysaccharide)6A CPS (Streptococcus pneumoniae serotype 6A capsular polysaccharide)CPS 18C (Streptococcus pneumoniae capsular polysaccharide serotype 18C)19A CPS (Streptococcus pneumoniae serotype 19A capsular polysaccharide)CPS Type 20 (Streptococcus pneumoniae serotype 20 capsular polysaccharide)7F CPS (Streptococcus pneumoniae serotype 7F capsular polysaccharide)CPS19F (Streptococcus pneumoniae capsular polysaccharide serotype 19F)11A CPS (Streptococcus pneumoniae serotype 11A capsular polysaccharide)33F CPS (Streptococcus pneumoniae serotype 33F capsular polysaccharide)CPS 22F (Streptococcus pneumoniae serotype 22F capsular polysaccharide)CPS14 (Streptococcus pneumoniae capsular polysaccharide serotype 14)Streptococcus pneumoniae capsular polysaccharide serotype 9V (PnPS 9V)12F CPS (Streptococcus pneumoniae serotype 12F capsular polysaccharide)CPS23F (Streptococcus pneumoniae capsular polysaccharide serotype 23F)CPS4 (Streptococcus pneumoniae capsular polysaccharide serotype 4)15B CPS (Streptococcus pneumoniae serotype 15B capsular polysaccharide)Type 2 CPS (Streptococcus pneumoniae serotype 2 capsular polysaccharide)CPS 9N (Streptococcus pneumoniae serotype 9N capsular polysaccharide)6B CPS (Streptococcus pneumoniae serotype 6B capsular polysaccharide)SpCPS1 (Streptococcus pneumoniae capsular polysaccharide serotype 1)PPS5 (Streptococcus pneumoniae capsular polysaccharide serotype 5)

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