Drug intelligence / Profile preview

27T51 + cemiplimab

Development stage
Unknown
Lead developer
Regeneron Pharmaceuticals
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

27T51 + cemiplimab is a combination drug consisting of an unspecified agent referred to as 27T51 and cemiplimab, a monoclonal antibody targeting the programmed death receptor-1 (PD-1). Cemiplimab acts as an immune checkpoint inhibitor by blocking the PD-1/PD-L1 pathway, thereby enhancing T-cell–mediated immune responses against tumors. Cemiplimab is developed primarily for oncology indications, including cutaneous squamous cell carcinoma, basal cell carcinoma, and non-small cell lung cancer. The nature, mechanism of action, or other properties of 27T51 are not defined in any available authoritative sources, and it does not correspond to a recognized pharmaceutical, investigational agent, or known code name in the literature or regulatory documentation[1][2][5][6].

Other names
cemiplimab-rwlc
02

Targets

PDCD1 (Programmed cell death protein 1 receptor)MUC16 (Mucin-16)

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