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3-(3,5-dibromo-4-hydroxybenzoyl)-2-ethyl-N-(4-sulfamoylphenyl)-1-benzofuran-6-sulfonamide
- Development stage
- Preclinical
- Modality
- Small Molecules
01
Overview
This compound is a synthetic small molecule inhibitor of protein tyrosine phosphatase 1B (PTP1B), an enzyme implicated in the negative regulation of insulin and leptin signaling. By inhibiting PTP1B activity, this molecule has been investigated as a potential therapeutic agent for metabolic disorders such as type 2 diabetes and obesity. It features a benzofuran core substituted with dibromohydroxybenzoyl and sulfamoylphenyl groups. The compound is primarily used in research settings to study the modulation of PTP1B activity and its downstream effects on cellular signaling pathways[1][2][5].
- Other names
- 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide959324-50-6SCHEMBL20817061SCHEMBL-20817061SCHEMBL 20817061
02
Targets
PTPN1 (Protein tyrosine phosphatase 1B)
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