Drug intelligence / Profile preview

3D124

Development stage
Unknown
Lead developer
3D Medicines
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
01

Overview

3D124 is an mRNA-based cancer vaccine developed by 3D Medicines for the treatment of various solid tumors. The vaccine is designed to encode tumor-specific neoantigens, which are unique proteins resulting from somatic mutations in cancer cells. By introducing these mRNA sequences into the body, 3D124 aims to activate the patient's immune system, specifically eliciting neoantigen-specific T-cell responses to recognize and eliminate tumor cells. It is currently in Phase 1 clinical development.

02

Targets

Neuroblastoma RAS viral oncogene homolog (NRAS) neoantigen-derived peptide

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