Drug intelligence / Profile preview

3Z-20-003

Development stage
Preclinical
Lead developer
3Z Pharmaceuticals
Modality
Small Molecules
01

Overview

**3Z-20-003** is a repurposed **small molecule** **L-type calcium channel blocker** developed by **3Z Pharmaceuticals** (also referred to as 3Z ehf) for **attention deficit hyperactivity disorder (ADHD)**. It has demonstrated proof-of-concept in **zebrafish** behavioral screening models and **rodent** models, as well as supportive **in silico** data, positioning it as a candidate for neurological indications via the **505(b)(2) NDA** pathway in the US and **Article 8(3)/10** in the EU. The drug targets **L-type calcium channels**, which play a critical role in neuronal excitability and signaling, potentially offering a novel mechanism for ADHD treatment.

Other names
3Z 20 003
02

Targets

CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)

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