Drug intelligence / Profile preview

4-hydroxy-1,2,5-oxadiazole-3-carboxylic acid

Development stage
Unknown
Modality
Small Molecules
01

Overview

4-hydroxy‑1,2,5‑oxadiazole‑3‑carboxylic acid is a small molecule belonging to the class of furazans (also known as oxadiazoles), characterized by a five-membered heterocyclic ring containing nitrogen and oxygen atoms. It has the molecular formula C₃H₂N₂O₄ and is primarily used in research settings. The compound has been identified as an experimental drug with no approved medical indications or clinical trial activity beyond preclinical investigation. It is known to interact with L-lactate dehydrogenase and L-lactate dehydrogenase B chain in biochemical studies; however, its precise mechanism of action remains uncharacterized[1][2][4]. There are no reported therapeutic uses or marketed products containing this compound.

Other names
4-Hydroxy-furazan-3-carboxylic acid4-Oxo-1,2,5-oxadiazole-3-carboxylic acid4-Oxo-4,5-dihydro-1,2,5-oxadiazole-3-carboxylic acid66313–36–8
02

Targets

LDH (L-lactate dehydrogenase A chain)PfLDH (Plasmodium falciparum lactate dehydrogenase)

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