4-methylaminorex

**4-methylaminorex** is a synthetic stimulant drug of the 2-amino-5-aryloxazoline class, first synthesized in 1960 by McNeil Laboratories as a potential appetite suppressant. It acts primarily as an indirect sympathomimetic agent, stimulating the release of dopamine and norepinephrine, and to a lesser extent serotonin, by interacting with monoamine transporters. This results in increased alertness, euphoria, cognitive enhancement, and reinforcing properties similar to amphetamines and cocaine but with a longer duration of action. The drug exists as four stereoisomers (cis and trans forms), with varying potency; the trans-(4S,5S) isomer is most potent. Although initially investigated for medical use (notably appetite suppression), its development was discontinued in favor of aminorex due to safety concerns. Today it is classified as a Schedule I substance in many countries due to its abuse potential[1][6][7].

Brand names

U4EuhU-4EuhU 4EuhEuphoriaICEIntellex

Other names

4MA