Drug intelligence / Profile preview

4-valent human papillomavirus recombinant vaccine (hansenula polymorpha)

Development stage
Unknown
Lead developer
Shanghai Bovax Biotechnology
Modality
Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

The 4-valent human papillomavirus recombinant vaccine (Hansenula polymorpha) is an investigational **prophylactic quadrivalent HPV vaccine** developed by Shanghai Bovax Biotechnology. It contains purified virus-like particles formed from recombinant L1 major capsid proteins of HPV types 6, 11, 16, and 18 expressed in *Hansenula polymorpha* and adsorbed to an aluminium adjuvant. Vaccination is intended to induce neutralizing anti-L1 immune responses that prevent infection and HPV-associated cervical and vaginal precancerous lesions, cervical cancer, and genital warts caused by the covered HPV types. The program has entered Phase 3 clinical development in Chinese female populations. ([m.bovaxbio.com](https://m.bovaxbio.com/en/sys-pd/2.html))

Other names
4-valent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine (hansenula polymorpha)4-valent human papillomavirus recombinant vaccine (hansenula polymorpha)quadrivalent human papillomavirus (types 6, 11, 16, 18) recombinant vaccine (hansenula polymorpha)quadrivalent human papillomavirus recombinant vaccine (hansenula polymorpha)
02

Targets

HPV16 (Human papillomavirus type 16)HPV6 L1 (Human papillomavirus type 6 major capsid protein L1)HPV11 L1Human papillomavirus type 18 major capsid protein L1

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