4HBAP

4HBAP, also known as para-topolin, is an aromatic cytokinin small molecule developed by Pyratine LLC for dermatological applications. As a plant growth regulator, it has been adapted for human skin care due to its ability to delay cellular senescence and provide antioxidant effects. It is typically used in topical formulations at a 0.10% concentration to treat signs of facial photodamage, including fine lines, coarse wrinkles, skin roughness, and hyperpigmentation. Clinical studies have also demonstrated its efficacy in reducing facial erythema and non-inflammatory acne lesions. 4HBAP is noted for its ability to enhance skin hydration and barrier function without the irritation or side effects often associated with traditional anti-aging treatments like retinoids.

Brand names

Pyratine XR

Other names

para-topolin6-(4-hydroxybenzylamino) purinep-topolin6-(4-hydroxybenzylamino)purine